Failure in Salt-Sensitive Hypertensive Rats Ventricles During the Transition From Compensatory Hypertrophy to Congestive Heart Cardiac Endothelin-1 Plays a Critical Role in the Functional Deterioration of Left
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Yoshitaka Iwanaga, Yasuki Kihara, Koji Hasegawa, Koichi Inagaki, Takeshi Yoneda, Satoshi Failure in Salt-Sensitive Hypertensive Rats Ventricles During the Transition From Compensatory Hypertrophy to Congestive Heart Cardiac Endothelin-1 Plays a Critical Role in the Functional Deterioration of Left Print ISSN: 0009-7322. Online ISSN: 1524-4539 Copyright © 1998 American Heart Association, Inc. All rights reserved. is published by the American Heart Association, 7272 Greenville Avenue, Dallas, TX 75231 Circulation doi: 10.1161/01.CIR.98.19.2065 1998;98:2065-2073 Circulation. http://circ.ahajournals.org/content/98/19/2065 World Wide Web at: The online version of this article, along with updated information and services, is located on the
منابع مشابه
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BACKGROUND In view of their mutual crosstalk, the roles of angiotensin II (Ang II) and endothelin-1 (ET-1) in the myocardium are assumed to be synergistic and supplemental. METHODS AND RESULTS In the phase of compensated left ventricular (LV) hypertrophy of Dahl salt-sensitive rats, Ang II peptide and the ACE mRNA in the LV were increased by 1.6- and 3.8-fold, respectively. In contrast, ET-1 ...
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تاریخ انتشار 1998